ChemicalBook > CAS DataBase List > 1,2,3,4-TETRAHYDRO-2-(TRIFLUOROACETYL)ISOQUINOLINE-7-SULFONYL CHLORIDE

1,2,3,4-TETRAHYDRO-2-(TRIFLUOROACETYL)ISOQUINOLINE-7-SULFONYL CHLORIDE

Product Name
1,2,3,4-TETRAHYDRO-2-(TRIFLUOROACETYL)ISOQUINOLINE-7-SULFONYL CHLORIDE
CAS No.
74291-57-9
Chemical Name
1,2,3,4-TETRAHYDRO-2-(TRIFLUOROACETYL)ISOQUINOLINE-7-SULFONYL CHLORIDE
Synonyms
ethyl 2-(6-hydroxypyridin-3-yl)acetate;1,2,3,4-Tetrahydro-2-(2,2,2-trifluoroacetyl)-;1,2,3,4-Tetrahydro-2-(trifluoroacetyl)isoquinoline-7-sulfon;Tetrahydro-2-(trifluoroacetyl)isoquinoline-7-sulfonyl chloride;2-(Trifluoroacetyl)-1,2,3,4-tetrahydro-7-isoquinolinesulfonyl chloride;1,2,3,4-TETRAHYDRO-2-(TRIFLUOROACETYL)ISOQUINOLINE-7-SULFONYL CHLORIDE;1,2,3,4-TETRAHYDRO-2-(TRIFLUOROACETYL)ISOQUINOLINE-7-SULPHONYL CHLORIDE;2-Trifluoroacetyl-1,2,3,4-tetrahydroisoquinoline-7-sulfonyl chloride, 99%;2-(2,2,2-Trifluoroacetyl)-1,2,3,4-tetrahydroisoquinoline-7-sulfonyl chloride;7-Isoquinolinesulfonyl chloride, 1,2,3,4-tetrahydro-2-(2,2,2-trifluoroacetyl)-
CBNumber
CB1365764
Molecular Formula
C11H9ClF3NO3S
Formula Weight
327.71
MOL File
74291-57-9.mol
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1,2,3,4-TETRAHYDRO-2-(TRIFLUOROACETYL)ISOQUINOLINE-7-SULFONYL CHLORIDE Property

Melting point:
102-104°C
Boiling point:
465.6±45.0 °C(Predicted)
Density 
1.548±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
-2.07±0.20(Predicted)
Sensitive 
Moisture Sensitive
BRN 
5603124
CAS DataBase Reference
74291-57-9
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Safety

Risk Statements 
34
Safety Statements 
26-36/37/39-45
RIDADR 
3261
HazardClass 
8
PackingGroup 
II
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

H318Causes serious eye damage

Precautionary statements

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Alfa Aesar
Product number
L13587
Product name
2-Trifluoroacetyl-1,2,3,4-tetrahydroisoquinoline-7-sulfonyl chloride, 99%
Packaging
5g
Price
$141.65
Updated
2024/03/01
TRC
Product number
T295790
Product name
1,2,3,4-Tetrahydro-2-(trifluoroacetyl)isoquinoline-7-sulfonylChloride
Packaging
2.5g
Price
$155
Updated
2021/12/16
Matrix Scientific
Product number
093871
Product name
2-(2,2,2-Trifluoroacetyl)-1,2,3,4-tetrahydro-isoquinoline-7-sulfonyl chloride
Purity
98%
Packaging
5g
Price
$252
Updated
2021/12/16
AK Scientific
Product number
0937AP
Product name
2-(2,2,2-Trifluoro-acetyl)-1,2,3,4-tetrahydro-isoquinoline-7-sulfonylchloride,tech.
Packaging
1g
Price
$49
Updated
2021/12/16
Matrix Scientific
Product number
093871
Product name
2-(2,2,2-Trifluoroacetyl)-1,2,3,4-tetrahydro-isoquinoline-7-sulfonyl chloride
Purity
98%
Packaging
1g
Price
$95
Updated
2021/12/16
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1,2,3,4-TETRAHYDRO-2-(TRIFLUOROACETYL)ISOQUINOLINE-7-SULFONYL CHLORIDE Chemical Properties,Usage,Production

Uses

1,2,3,4-Tetrahydro-2-(trifluoroacetyl)isoquinoline-7-sulfonyl Chloride is an intermediate for the preparation of 5-heteroaryl thiazoles and their use as phosphoinositide 3-kinase (PI3K) inhibitors.

1,2,3,4-TETRAHYDRO-2-(TRIFLUOROACETYL)ISOQUINOLINE-7-SULFONYL CHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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1,2,3,4-TETRAHYDRO-2-(TRIFLUOROACETYL)ISOQUINOLINE-7-SULFONYL CHLORIDE Suppliers

Canada 1 China 29 Germany 2 India 3 The Netherlands 1 United Kingdom 1 United States 7 Global 44

74291-57-9, 1,2,3,4-TETRAHYDRO-2-(TRIFLUOROACETYL)ISOQUINOLINE-7-SULFONYL CHLORIDERelated Search:

Trifluoromethanesulfonic acid Isoquinoline N-(2,2,2-TRIFLUOROETHYL)BENZENEETHANAMINE HYDROCHLORIDE N-(2,2,2-TRIFLUOROETHYL)BENZENEMETHANAMINE HYDROCHLORIDE N,N-DIMETHYLTRIFLUOROACETAMIDE 4-Ethylbenzene-1-sulfonyl chloride N,N-DIETHYL-2,2,2-TRIFLUOROACETAMIDE p-(2-acetamidoethyl)benzenesulphonyl chloride 1,2,3,4-TETRAHYDRO-2-(TRIFLUOROACETYL)ISOQUINOLINE-7-SULFONYL CHLORIDE N-BENZYL-2,2,2-TRIFLUORO-ACETAMIDE 4,4'-DIMETHYLBIPHENYL

  • 1,2,3,4-TETRAHYDRO-2-(TRIFLUOROACETYL)ISOQUINOLINE-7-SULFONYL CHLORIDE
  • 1,2,3,4-TETRAHYDRO-2-(TRIFLUOROACETYL)ISOQUINOLINE-7-SULPHONYL CHLORIDE
  • 2-(trifluoroacetyl)-1,2,3,4-tetrahydro-7-isoquinolinesulfonyl chloride(SALTDATA: FREE)
  • 1,2,3,4-Tetrahydro-2-(2,2,2-trifluoroacetyl)-
  • 2-(2,2,2-Trifluoroacetyl)-1,2,3,4-tetrahydroisoquinoline-7-sulfonyl chloride
  • 2-Trifluoroacetyl-1,2,3,4-tetrahydroisoquinoline-7-sulfonyl chloride, 99%
  • 2-(Trifluoroacetyl)-1,2,3,4-tetrahydro-7-isoquinolinesulfonyl chloride
  • Tetrahydro-2-(trifluoroacetyl)isoquinoline-7-sulfonyl chloride
  • ethyl 2-(6-hydroxypyridin-3-yl)acetate
  • 7-Isoquinolinesulfonyl chloride, 1,2,3,4-tetrahydro-2-(2,2,2-trifluoroacetyl)-
  • 1,2,3,4-Tetrahydro-2-(trifluoroacetyl)isoquinoline-7-sulfon
  • 74291-57-9
  • C11H9ClF3NO3S
  • Aromatics
  • Heterocycles
  • Inhibitors
  • Sulfur & Selenium Compounds